Estimating Australian Population Utilities for Inherited Retinal Disease Using Time Trade-Off.

ABSTRACT:

Purpose

Inherited retinal disease (IRD) causes progressive loss of visual function, degenerating towards complete blindness. Economic evaluation of gene therapies for rare forms of genetic IRDs have had to rely on health-related quality of life (HR-QoL) estimates from other diseases because there is limited data available for such a rare condition. This study aimed to estimate Australian societal-based utility values for IRD health states that can be used in cost-utility analyses (CUA) using a time trade-off (TTO) protocol adapted from a UK study.

Methods

The EuroQol Valuation Technology (EQVT) protocol composite TTO (cTTO) framework was followed, which includes worse-than-death (WTD) states and quality control (QC) measures. Preferences were collected from a general populat

SUBMITTER: Farris M 

PROVIDER: S-EPMC11499549 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature