Preliminary proteomic analysis of mouse lung tissue treated with cyclophosphamide and Venetin-1.

ABSTRACT: Cyclophosphamide (CPAm) is a widely used chemotherapeutic agent that exhibits potent anti-cancer properties but is often associated with debilitating side effects. Despite its efficacy, the management of CPAm-induced toxicities remains a significant clinical challenge. There has been growing interest in exploring complementary and alternative therapies to mitigate these adverse effects in recent years, and this may be a chance for the earthworm-derived preparation, Venetin-1. Its rich composition of bioactive compounds has demonstrated promising pharmacological properties, including anti-inflammatory, antioxidant, and immunomodulatory effects. These properties suggest its potential to counteract various systemic toxicities induced by CPAm. We conducted a comprehensive study to investigate

SUBMITTER: Czaplewska P 

PROVIDER: S-EPMC11499674 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature