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Accelerated Nanocomposite Hydrogel Gelation Times Independent of Gold Nanoparticle Ligand Functionality.


ABSTRACT: The expansive use of hydrogels in healthcare relies on carefully tuned properties in dynamic environments with predictable behavior, including time sensitive biological systems and biomedical applications. To meet demands in these settings, nanomaterials are often introduced to a hydrogel matrix which simultaneously elevates potential applications while adding complexity to fundamental characteristics. With respect to drug delivery, gold nanoparticles have modifiable surfaces to carry an array of targeted drug treatments. However, different molecules acting as capping ligands possess different chemical structures that can impact gelation times. To understand the influence of capping ligand chemistry on polyacrylamide (PAM) based nanocomposite hydrogel radical gelation time, gold nanopartic

SUBMITTER: Couturier B 

PROVIDER: S-EPMC11500131 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature