Sex differences in distributed error-related neural activation in problem-drinking young adults.

ABSTRACT:

Background

Detecting and responding to errors is central to goal-directed behavior and cognitive control and is thought to be supported by a network of structures that includes the anterior cingulate cortex and anterior insula. Sex differences in the maturational timing of cognitive control systems create differential periods of vulnerability for psychiatric conditions, such as substance use disorders.

Methods

We examined sex differences in error-related activation across an array of distributed brain regions during a Go/No-Go task in young adults with problem alcohol use (N=69; 34 females; M=19.4 years). Regions of interest previously linked to error-related activation, including anterior cingulate cortex, insula, and frontoparietal structures, were selected in a term-based

SUBMITTER: Hardee JE 

PROVIDER: S-EPMC11500318 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature