The opioid industry's use of scientific evidence to advance claims about prescription opioid safety and effectiveness.

ABSTRACT: It is widely recognized that pharmaceutical marketing contributed to the ongoing US opioid epidemic, but less is understood about how the opioid industry used scientific evidence to generate product demand, shape opioid regulation, and change clinician behavior. In this qualitative study, we characterize select scientific articles used by industry to support safety and effectiveness claims and use a novel database, the Opioid Industry Documents Archive, to determine notable elements of industry and non-industry documents citing the scientific articles to advance each claim. We found that 15 scientific articles were collectively mentioned in 3666 documents supporting 5 common, inaccurate claims: opioids are effective for treatment of chronic, non-cancer pain; opioids are "rarely" addictive;

SUBMITTER: Gupta R 

PROVIDER: S-EPMC11500661 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature