Hybrid plasmonic nanodiamonds for thermometry and local photothermal therapy of melanoma: a comparative study.

ABSTRACT: Hyperthermia plays a significant role in cancer treatment by inducing cell damage through temperature elevation, often used alongside other treatment modalities. During hyperthermia therapy, temperature control is crucial. Here, we report on a simple synthesis route of hybrid plasmonic nanodiamonds either completely wrapped with an Au shell (NV@Au) or densely covered with Au NPs (NV@SiO ₂ @Au). Such integration of nanodiamonds with Au NPs is advantageous both for heating and precise thermometry at nanoscale. After structural and optical investigations, heating abilities of the obtained plasmonic nanodiamonds were thoroughly inspected on glass, in association with living cells, and in tissue slices ex vivo, revealing their effective heat generat

SUBMITTER: Gerasimova EN 

PROVIDER: S-EPMC11501064 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature