Terahertz virus-sized gold nanogap sensor.

ABSTRACT: We demonstrated an ultra-sensitive terahertz virus detection method combined with virus-sized gold nanogaps filled with Al₂O₃. Large-area high-density 20 nm-gap rectangular loop structures, containing a resonant frequency in the terahertz range, were fabricated on a 4-inch wafer using atomic layer lithography. When target viruses with a 60 nm diameter were located on the nanogaps, we observed a significant redshift of the resonant peak already with an average number of about 100 viruses per unit loop due to the strong field confinement and enhancement near the gap. Furthermore, when the virus was tightly attached to an etched gap like a bridge connecting metals, its sensitivity is doubled compared to the unetched gap, which resulted in 400% more resonance frequency sh

SUBMITTER: Ji G 

PROVIDER: S-EPMC11501242 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature