Fluorescence engineering in metamaterial-assisted super-resolution localization microscope.

ABSTRACT: Single-molecule localization microscopies have gained much attention for their efficient realization of a sub-diffraction-limit imaging with the resolution down to the 10-nm range. In contrast to conventional localization microscopes, which rely on particular fluorescent probes in specific conditions, metamaterial-assisted super-resolution microscopies can be implemented with any fluorescent dye under general conditions. Here, we present a systematic study of fluorescence engineering in metamaterial assisted localization microscopy by using cyclic group metasurfaces coated with a fluorescent film. Tailored variations are clearly demonstrated in both the photoluminescence intensity and the photobleaching lifetime of fluorophores based on the spatially varied Purcell effect near the metasurf

SUBMITTER: Choi KR 

PROVIDER: S-EPMC11501635 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature