Balancing selection shapes population differentiation of major histocompatibility complex genes in wild golden snub-nosed monkeys.

ABSTRACT: Small and isolated populations face several intrinsic risks, such as genetic drift, inbreeding depression, and reduced gene flow. Thus, patterns of genetic diversity and differentiation have become an important focus of conservation genetics research. The golden snub-nosed monkey Rhinopithecus roxellana, an endangered species endemic to China, has experienced rapid reduction in population size and severe population fragmentation over the past few decades. We measured the patterns of genetic diversity and population differentiation using both neutral microsatellites and adaptive major histocompatibility complex (MHC) genes in 2 R. roxellana populations (DPY and GNG) distributed on the northern and southern slopes of the Qinling Mountains, respectively. Eight MHC-linked haploty

SUBMITTER: Dong S 

PROVIDER: S-EPMC11502152 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature