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Vaginal dinoprostone insert compared with two different oral misoprostol regimens for labor induction in nulliparous and multiparous women.


ABSTRACT:

Introduction

Labor induction exhibits considerable variations in protocols and medication regimens. Limited studies compare vaginal dinoprostone inserts with different oral misoprostol dosages, considering parity influence. This study explores the distinctions among 10 mg vaginal dinoprostone inserts and oral misoprostol 25 μg every 2 and every 4 h for labor induction, stratified by parity.

Material and methods

This retrospective cohort study involved 607 participants across two hospitals. The primary outcome, time from induction to delivery, and secondary outcomes, including mode of delivery and maternal and fetal safety, were assessed.

Results

Patient characteristics revealed differences in indication for labor induction, with the dinoprostone cohort having fewer po

SUBMITTER: Erhardt D 

PROVIDER: S-EPMC11502454 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature