Altered brain texture features in end-stage renal disease patients: a voxel-based 3D brain texture analysis study.

ABSTRACT:

Introduction

Cognitive impairment in patients with end-stage renal disease (ESRD) is associated with brain structural damage. However, no prior studies have investigated the relationship between brain texture features and the cognitive function in ESRD patients. This study aimed to investigate changes in brain texture features in ESRD patients and their relationships with cognitive function using voxel-based 3D brain texture analysis (TA), and further predict individual cognitive-related brain damage in ESRD patients.

Methods

Forty-seven ESRD patients and 45 control subjects underwent whole-brain high-resolution 3D T1-weighted imaging scans and neuropsychological assessments. The voxel-based 3D brain TA was performed to examine inter-group differences in brain texture featur

SUBMITTER: Fang J 

PROVIDER: S-EPMC11502495 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature