Practical Application of Multivendor MRI-Based R2* Mapping for Liver Iron Quantification at 1.5 T and 3.0 T.

ABSTRACT:

Background

Recent multicenter, multivendor MRI-based R2* vs. liver iron concentration (LIC) calibrations (i.e., MCMV calibrations) may facilitate broad clinical dissemination of R2*-based LIC quantification. However, these calibrations are based on a centralized offline R2* reconstruction, and their applicability with vendor-provided R2* maps is unclear.

Purpose

To determine R2* ranges of agreement between the centralized and three MRI vendors' R2* reconstructions.

Study type

Prospective.

Subjects

Two hundred and seven subjects (mean age 37.6 ± 19.6 years; 117 male) with known or suspected iron overload from four academic medical centers.

Field strength/sequence

Standardized multiecho spoiled gradient echo sequence at 1.5 T and 3.0 T for R2* mapping and

SUBMITTER: Simchick G 

PROVIDER: S-EPMC11502507 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature