Young hearts, early risks: novel cardiovascular biomarkers in former very preterm infants at kindergarten age.

ABSTRACT:

Background

Preterm birth is associated with long-term cardiovascular morbidity and mortality. In adults, fibroblast growth factor-23 (FGF-23), α-Klotho, and secretoneurin have all garnered attention as cardiovascular biomarkers, but their utility in pediatric populations has not yet been ascertained. The aim of this pilot study was to evaluate these novel cardiovascular biomarkers and their association with indicators of cardiovascular impairment in the highly vulnerable population of former very preterm infants.

Methods

Five- to seven-year-old children born at < 32 weeks' gestation were eligible for the study. Healthy same-aged children born at term served as controls. Biomarkers were quantified in fasting blood samples, and echocardiographic measurements including assessme

SUBMITTER: Mitterer W 

PROVIDER: S-EPMC11502516 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature