Molecular characterization, phylogenetic and variation analyses of SARS-CoV-2 strains in India.

ABSTRACT: In the wake of the havoc caused by the COVID-19 pandemic, it is imperative to use the available genomic sequence data to gain insight into the mutational and genomic diversity of SARS-CoV-2. Here we have performed comparative phylogenetic, mutational and genetic diversity analysis on 1962 SARS-CoV-2 genome sequences from seven worst hit Indian states during the third Covid-19 wave, to determine the SARS-CoV-2 strains and mutations in circulation during the third wave and the transmission pattern and disease epidemiology across the states and gain valuable insight into the viral evolution. 6083 Single nucleotide polymorphisms (SNPs) were discovered in the analysis with 93 SNPs common to all states. The genetic relatedness among the statewise multilocus genotypes was visualized by plotting a

SUBMITTER: Banerjee M 

PROVIDER: S-EPMC11502728 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature