Association of left ventricular ejection fraction with risk of cardiovascular diseases: a prospective cohort study.

ABSTRACT: Left ventricular ejection fraction (LVEF) is the most ubiquitous parameter in cardiac imaging examinations, we aimed to investigate the associations between subtle changes of LVEF and risk of common cardiovascular diseases. This is a prospective cohort study based on UK Biobank. LVEF was obtained from cardiac magnetic resonance. Incident cardiovascular disease was the outcome, including heart failure, atrial fibrillation, ischemic heart disease, and myocardial infarction. Cox proportional hazard model was the main method. A U-shaped relationship was observed between quantified LVEF and cardiovascular events risk with the nadir at the LVEF of 55-64%. As compared to moderate LVEF (55-64%), both low (40-54%) and high LVEF ( ≥ 5%) were related to higher risk of cardiovascular diseases after ad

SUBMITTER: Xiao J 

PROVIDER: S-EPMC11502777 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature