The ASAP study: association of atherosclerosis with pathobiology in a caucasian cohort-a study of 3400 autopsy reports.

ABSTRACT: Cardiovascular plaques result from atherosclerosis. Autopsy investigations of unnatural deaths provide atherosclerosis research. A Central European cohort was studied in a cross-sectional study to determine the origin of atherosclerosis and the link between arterial status and pathobiological variables. This study incorporated 3400 autopsy reports (n = 2318 men; aged 0─96 years; 1928─2010) of persons who died by unnatural causes (suicide, homicide, accident). Age, sex, BMI, abdominal fat thickness, and arterial status of six vascular areas were gathered. The arterial state was divided into five subgroups according to its status. BMI declined from 22.82 kg/m2 in 1931 to 18.43 kg/m² in 1947, then increased to 27.88 kg/m² in 2005. Atherosclerotic degeneration begins in t

SUBMITTER: Jakab AE 

PROVIDER: S-EPMC11502792 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature