Impact of commonly administered drugs on the progression of spinal cord injury: a systematic review.

ABSTRACT:

Background

Complications arising from acute traumatic spinal cord injury (SCI) are routinely managed by various pharmacological interventions. Despite decades of clinical application, the potential impact on neurological recovery has been largely overlooked. This study aims to highlight commonly administered drugs with potential disease-modifying effects.

Methods

This systematic literature review included studies referenced in PubMed, Scopus and Web of Science from inception to March 31st, 2021, which assess disease-modifying properties on neurological and/or functional recovery of drugs routinely administered following spinal cord injury. Drug effects were classified as positive, negative, mixed, no effect, or not (statistically) reported. Risk of bias was assessed separate

SUBMITTER: Bourguignon L 

PROVIDER: S-EPMC11502874 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature