Achieved oxygen saturations and risk for bronchopulmonary dysplasia with pulmonary hypertension in preterm infants.

ABSTRACT:

Objective

Characterisation of oxygen saturation (SpO₂)-related predictors that correspond with both bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) development and survival status in infants with BPD-PH may improve patient outcomes. This investigation assessed whether (1) infants with BPD-PH compared with infants with BPD alone, and (2) BPD-PH non-survivors compared with BPD-PH survivors would (a) achieve lower SpO₂ distributions, (b) have a higher fraction of inspired oxygen (FiO₂) exposure and (c) have a higher oxygen saturation index (OSI).

Design

Case-control study between infants with BPD-PH (cases) and BPD alone (controls) and by survival status within cases.

Setting

Single-centre study in the USA.

Patien

SUBMITTER: Gentle SJ 

PROVIDER: S-EPMC11503043 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature