Environmental exposures associated with early childhood recurrent wheezing in the mother and child in the environment birth cohort: a time-to-event study.

ABSTRACT:

Background

Antenatal factors and environmental exposures contribute to recurrent wheezing in early childhood.

Aim

To identify antenatal and environmental factors associated with recurrent wheezing in children from birth to 48 months in the mother and child in the environment cohort, using time-to-event analysis.

Method

Maternal interviews were administered during pregnancy and postnatally and children were followed up from birth to 48 months (May 2013-October 2019). Hybrid land-use regression and dispersion modelling described residential antenatal exposure to nitrogen dioxide (NO₂) and particulate matter of 2.5 µm diameter (PM_2.5). Wheezing status was assessed by a clinician. The Kaplan-Meier hazard function and Cox-proportional hazard models pr

SUBMITTER: Asharam K 

PROVIDER: S-EPMC11503139 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature