Respiratory outcomes and survival after unplanned extubation in the NICU: a prospective cohort study from the SEPREVEN trial.

ABSTRACT:

Objective

To compare reintubation rates after planned extubation and unplanned extubation (UE) in patients in neonatal intensive care units (NICUs), to analyse risk factors for reintubation after UE and to compare outcomes in patients with and without UE.

Design

Prospective, observational study nested in a randomised controlled trial (SEPREVEN/Study on Epidemiology and PRevention of adverse EVEnts in Neonates). Outcomes were expected to be independent of the intervention tested.

Setting

12 NICUs in France with a 20-month follow-up, starting November 2015.

Patients

n=2280 patients with a NICU stay >2 days, postmenstrual age ≤42 weeks on admission.

Interventions/exposure

Characteristics of UE (context, timing, sedative administration in the preceding 6 hou

SUBMITTER: Yager H 

PROVIDER: S-EPMC11503181 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature