Extranodal extension influences prognosis in pancreatic body/tail cancer: A retrospective cohort study.

ABSTRACT:

Background/purpose

Extranodal extension (ENE) is an established prognostic factor in various malignancies, affecting survival in pancreatic head cancer (PHC). However, its significance in pancreatic body/tail cancer (PBTC) remains unclear. Therefore, we aimed to investigate the impact of ENE on PTBC prognosis.

Methods

We analyzed data collected from electronic medical records of patients with PBTC who underwent distal pancreatectomy at a single center between January 2011 and December 2015. The patients were categorized based on ENE presence and prognostic implications were evaluated using Kaplan-Meier survival curves and Cox proportional hazards model.

Results

PBTC cases involving lymph node (LN) metastasis and ENE exhibited significantly lower disease-free (DFS) and

SUBMITTER: Sung MK 

PROVIDER: S-EPMC11503450 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature