Real-world evidence of systemic treatment practices for biliary tract cancer in Japan: Results of a database study.

ABSTRACT:

Purpose

To describe the real-world treatment patterns of systemic therapies for biliary tract cancer (BTC) and to examine the frequency and management of biliary infection in Japan.

Methods

Patients diagnosed with BTC and prescribed systemic therapy between January 2011 and September 2020 were retrieved from the Japanese Medical Data Vision database. The look-back period was set to 5 years. Patient characteristics, treatment patterns, and biliary infection-induced treatment interruption were analyzed.

Results

The full analysis set comprised 22 742 patients with a mean age of 71.0 years and 61.6% were male. The most common BTC type was extrahepatic cholangiocarcinoma (44.6%). The three most common first-line regimens were S-1 monotherapy (33.0%), gemcitabine+cisplatin

SUBMITTER: Ueno M 

PROVIDER: S-EPMC11503459 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature