Whole-Transcriptome Analysis Reveals Potential CeRNA Regulatory Mechanism in <i>Takifugu rubripes</i> against <i>Cryptocaryon irritans</i> Infection.

ABSTRACT: Cryptocaryon irritans (C. irritans) is a proto-ciliate parasite that infects marine fishes, including the cultured species Takifugu rubripes (T. rubripes), causing disease and potential mortality. In host organisms, infection by parasites triggers an immune response that is modulated by regulatory elements including proteins and non-coding RNAs. In this study, the whole transcriptome RNA sequencing of T. rubripes gill tissue before and after infection with C. irritans was performed to reveal the competitive endogenous RNA (ceRNA) regulatory network. Histomorphology revealed gill segment swelling and parasitic invasion in the infected group. The analysis identified 18 differentially expressed miRNAs (DEMs), 214 lncRNAs (DELs), 2501 genes (DEGs), and

SUBMITTER: Xia Y 

PROVIDER: S-EPMC11504436 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature