Bioactivities of Quinic Acids from Vitex rotundifolia Obtained by Supercritical Fluid Extraction.

ABSTRACT: Acyl-quinic acids (AQAs), present in various plants with many health benefits, are regarded as therapeutic agents in the prevention and treatment of chronic and cardiovascular diseases. The molecular network-guided identification of ten AQA compounds, two new (5 and 7) and eight known compounds, were isolated from V. rotundifolia L. f. by using a newly applied extraction method. Their structures were determined through spectroscopic means, reaction mixtures, and modified Mosher and PGME techniques. These compounds were assessed for their anti-inflammatory and antioxidant capabilities. Notably, compounds 1, 3, 4, 6, 8, and 9 exhibited notable DPPH radical scavenging activity. In LPS-induced HT-29 cells, compounds 2-7</

SUBMITTER: Le DD 

PROVIDER: S-EPMC11504455 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature