Dietary insulin index and dietary insulin load in relation to non-alcoholic fatty liver disease: a cross-sectional study.

ABSTRACT:

Objective

Postprandial hyperinsulinaemia plays a key role in the development of non-alcoholic fatty liver disease (NAFLD). Diet is a potential factor affecting serum insulin levels. This study aimed to examine the relations of dietary insulin index (DII) and dietary insulin load (DIL) to the risk of NAFLD.

Design

This study was a cross-sectional study. DII and DIL were calculated using the dietary data obtained from the FFQ. Fatty liver index ≥ 60 and the confirmation of a gastroenterologist were required to diagnose NAFLD.

Setting

Community-based study.

Participants

A total of 3158 people (46·7 % male), aged 40·57 ± 8·25 years, participated in this study in Tehran, Iran from April 2016 to December 2019.

Results

The prevalence of NAFLD was 29·9 % (21·59

SUBMITTER: Motamedi A 

PROVIDER: S-EPMC11504692 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature