Different Oxidative Stress and Inflammation Patterns of Diseased Left Anterior Descending Coronary Artery versus Internal Thoracic Artery.

ABSTRACT:

Background

Oxidative stress and inflammation are typically implied in atherosclerosis pathogenesis and progression, especially in coronary artery disease (CAD). Our objective was to investigate the oxidative stress and inflammation burden directly associated with atherosclerotic plaque in patients with stable coronary disease undergoing coronary artery bypass graft (CABG) surgery. Specifically, markers of oxidative stress and inflammation were compared in blood samples obtained from the atherosclerotic left anterior descending artery (LAD) and blood samples obtained from the healthy left internal thoracic artery (LITA), used as a bypass graft, within the same patient.

Methods

Twenty patients scheduled for off-pump CABG were enrolled. Blood samples were collected from the LIT

SUBMITTER: Salica A 

PROVIDER: S-EPMC11505158 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature