The Association between Gut Microbiota and Serum Biomarkers in Children with Atopic Dermatitis.

ABSTRACT: Background. Currently, it is known that the gut microbiota plays an important role in the functioning of the immune system, and a rebalancing of the bacterial community can arouse complex immune reactions and lead to immune-mediated responses in an organism, in particular, the development of atopic dermatitis (AD). Cytokines and chemokines are regulators of the innate and adaptive immune response and represent the most important biomarkers of the immune system. It is known that changes in cytokine profiles are a hallmark of many diseases, including atopy. However, it remains unclear how the bacterial imbalance disrupts the function of the immune response in AD. Objectives. We attempted to determine the role of gut bacteria in modulating cytokine pathways and their role in ato

SUBMITTER: Kalashnikova IG 

PROVIDER: S-EPMC11505256 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature