Bacterial and Viral Co-Infections in COVID-19 Patients: Etiology and Clinical Impact.

ABSTRACT:

Background

Mixed infections can worsen disease symptoms. This study investigated the impact of mixed infections with viral and bacterial pathogens in patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Methods

Using the in-house multiplex PCR method, we tested 337 SARS-CoV-2 positive samples for co-infections with three bacterial and 14 other viral pathogens.

Results

Between August 2021 and May 2022, 8% of 337 SARS-CoV-2-positive patients had bacterial co-infections, 5.6% had viral co-infections, and 1.4% had triple mixed infections. The most common causes of mixed infections were Haemophilus influenzae (5.93%) and respiratory syncytial virus (RSV) (1.18%). Children < 5 years old had more frequent co-infections than adults < 65 y

SUBMITTER: Trifonova I 

PROVIDER: S-EPMC11505336 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature