Reduction of Blood Oxidative Stress Following Colorectal Cancer Resection.

ABSTRACT:

Background

Colorectal cancer is a major global health burden, with surgical resection being the standard treatment aimed at curative tumor removal. Oxidative stress plays a crucial role in colorectal cancer progression and prognosis. This study hypothesized that physical removal of colorectal cancer, a primary source of oxidative stress, would reduce blood levels of reactive oxygen metabolite derivatives (d-ROMs), a marker of oxidative stress, and biologic antioxidant potential (BAP) levels, a marker of antioxidant potential.

Methods

This study included 123 patients who underwent radical resection for colorectal cancer. d-ROM and BAP levels were measured before and one month after surgery.

Results

The clinicopathological analysis showed a correlation between preoperat

SUBMITTER: Sawai K 

PROVIDER: S-EPMC11505646 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature