Pathologic Outcomes and Survival in Patients with Rectal Cancer and Increased Body Mass Index.

ABSTRACT:

Introduction

We assessed the association between increased body mass index (BMI) and rectal cancer outcomes.

Methods

We included patients who underwent surgery for stage I-III rectal adenocarcinoma who were divided according to BMI at diagnosis: ideal BMI (18.5-24.9 kg/m2) and increased BMI (≥25 kg/m2). Groups were compared using univariate association analyses relative to baseline characteristics, pathologic outcomes, overall survival (OS), and disease-free survival (DFS). Main outcome measures involved circumferential resection margin (CRM), pathologic TNM stage, total mesorectal incision (TME) grade, OS, and DFS.

Results

243 patients (64.6% male; median age 59 years) with a median BMI of 26.3 kg/m2 were included. 62.1% had BMI ≥25 kg/m2. Increased BMI patients had

SUBMITTER: Emile SH 

PROVIDER: S-EPMC11506326 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature