Altered Gut Microbiota Patterns in Young Children with Recent Maltreatment Exposure.

ABSTRACT:

Background

The brain and the intestinal microbiota are highly interconnected and especially vulnerable to disruptions in early life. Emerging evidence indicates that psychosocial adversity detrimentally impacts the intestinal microbiota, affecting both physical and mental health. This study aims to investigate the gut microbiome in young children in the immediate aftermath of maltreatment exposure.

Methods

Maltreatment exposure was assessed in 88 children (ages 3-7) using the Maternal Interview for the Classification of Maltreatment [MICM]. Children were allocated to three groups according to the number of experienced maltreatment categories: no maltreatment, low maltreatment, and high maltreatment exposures. Stool samples were collected and analyzed by 16S rRNA sequencing.<

SUBMITTER: Karaboycheva G 

PROVIDER: S-EPMC11506340 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature