The Potential of Intra-Articular Therapies in Managing Knee Osteoarthritis: A Systematic Review.

ABSTRACT:

Background

Knee osteoarthritis (KOA) is a common degenerative and progressive joint disorder that negatively influences patients' quality of life. Intra-articular therapies, such as hyaluronic acid (HA) and platelet-rich plasma (PRP), have garnered attention for their potential to manage osteoarthritis OA symptoms effectively. This systematic review aims to identify the effectiveness and safety of HA and PRP treatment modalities in treating KOA.

Methods

A literature search was conducted across MEDLINE (PubMed), Web of Science Core Collection, and Science Direct Collection Elsevier. Twenty-three randomized controlled trials, cohort studies, and observational studies were included in the review. The selection criteria focused on studies published in English within the last 10

SUBMITTER: Pojala CV 

PROVIDER: S-EPMC11506573 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature