Development and Validation of a Diagnostic Algorithm for Down Syndrome Using Birth Certificate and International Classification of Diseases Codes.

ABSTRACT:

Objective

We aimed to develop an algorithm that accurately identifies children with Down syndrome (DS) using administrative data.

Methods

We identified a cohort of children born between 2000 and 2017, enrolled in the Tennessee Medicaid Program (TennCare), who either had DS coded on their birth certificate or had a diagnosis listed using an International Classification of Diseases (ICD) code (suspected DS), and who received care at Vanderbilt University Medical Center, a comprehensive academic medical center, in the United States. Children with suspected DS were defined as having DS if they had (a) karyotype-confirmed DS indicated on their birth certificate; (b) karyotype-pending DS indicated on their birth certificate (or just DS if test type was not specified) and at least

SUBMITTER: Ammar L 

PROVIDER: S-EPMC11506645 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature