Transcriptome and Metabolome Reveal Accumulation of Key Metabolites with Medicinal Properties of <i>Phylloporia pulla</i>.

ABSTRACT: Phylloporia pulla, a macrofungal species in the Hymenochaetales, Basidiomycota, is known to enhance the nutritional and bioactive properties of rice through co-fermentation; however, its own secondary metabolites are not well understood. In this study, an integrative analysis of transcriptome and metabolome data revealed that the accumulation of steroids, steroid derivatives, and triterpenoids in P. pulla peaks during the mid-growth stage, while the genes associated with these metabolites show higher expression levels from the early to mid-growth stages. Weighted gene co-expression network analysis identified several modules containing candidate genes involved in the synthesis of steroids, steroid derivatives, and triterpenoids. Specifically, six key hub genes w

SUBMITTER: Jiang JH 

PROVIDER: S-EPMC11507218 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature