Investigating the Antibacterial Effect of a Novel Gallic Acid-Based Green Sanitizer Formulation.

ABSTRACT: The purpose of the present study was to investigate the mechanism of action of our newly developed green sanitizer formulation comprising a natural phenolic compound, gallic acid (GA), strengthened by the Generally Recognized as Safe (GRAS) materials hydrogen peroxide (H₂O₂) and DL-lactic acid (LA). Combining 8 mM GA with 1 mM H₂O₂ resulted in an abundant generation of reactive oxygen species (ROS) and a bactericidal effect towards Gram-negative (Escherichia coli, Pseudomonas syringae, and Pectobacterium brasiliense) and Gram-positive (Bacillus subtilis) bacteria (4 to 8 log CFU mL^-1 reduction). However, the exposure to this dual formulation (DF) caused only a modest 0.7 log CFU mL^-1 reduction in

SUBMITTER: Mwangi EW 

PROVIDER: S-EPMC11507653 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature