Identification of Phospholipids Relevant to Cancer Tissue Using Differential Ion Mobility Spectrometry.

ABSTRACT: Phospholipids are the main building components of cell membranes and are also used for cell signaling and as energy storages. Cancer cells alter their lipid metabolism, which ultimately leads to an increase in phospholipids in cancer tissue. Surgical energy instruments use electrical or vibrational energy to heat tissues, which causes intra- and extracellular water to expand rapidly and degrade cell structures, bursting the cells, which causes the formation of a tissue aerosol or smoke depending on the amount of energy used. This gas phase analyte can then be analyzed via gas analysis methods. Differential mobility spectrometry (DMS) is a method that can be used to differentiate malignant tissue from benign tissues in real time via the analysis of surgical smoke produced by energy instrume

SUBMITTER: Sioris P 

PROVIDER: S-EPMC11508011 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature