Transcriptomic and Proteomic Analyses of the Immune Mechanism in Pathogenetic and Resistant Chinese Soft-Shelled Turtle (<i>Pelodiscus sinensis</i>) Infected with <i>Aeromonas hydrophila</i>.

ABSTRACT:

Background

As intensive aquaculture practices have progressed, the prevalence of bacterial diseases in the Chinese soft-shell turtle (Pelodiscus sinensis) has escalated, particularly infections caused by Aeromonas hydrophila, such as ulcerative dermatitis and abscess disease. Despite this, little is known about their immune defenses against this pathogen.

Methods

Our study pioneers an integrated analysis of transcriptomics and proteomics to investigate the immune responses of Chinese soft-shelled turtles to A. hydrophila infection.

Results

The investigation revealed significant differences in immune-related pathways between groups susceptible and resistant to A. hydrophila infection after 4 days. A total of 4667 and 3417 differentially expr

SUBMITTER: Ge L 

PROVIDER: S-EPMC11508015 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature