The Degradation of Absorbable Surgical Threads in Body Fluids: Insights from Infrared Spectroscopy Studies.

ABSTRACT: This study investigates the degradation of six different types of absorbable surgical threads commonly used in clinical practice, focusing on their response to exposure to physiological fluids. The threads were subjected to hydrolytic and enzymatic degradation in physiological saline, bile, and pancreatic juice. Our findings demonstrate that bile and pancreatic juice, particularly when contaminated with bacterial strains such as Escherichia coli, Klebsiella spp., and Enterococcus faecalis, significantly accelerate the degradation process. Using Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and tensile strength testing, we observed distinct differences in the chemical structure and mechanical integrity of the sutures. Principal comp

SUBMITTER: Merkel K 

PROVIDER: S-EPMC11508208 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature