Early high-sensitivity troponin elevation in predicting short-term mortality in sepsis: A protocol for a systematic review with meta-analysis.

ABSTRACT:

Background

Sepsis is a common admission diagnosis in the intensive care unit (ICU). The Sepsis-3 consensus associates sepsis diagnosis with acute organ dysfunction. In these patients troponin elevation is a well-established phenomenon, but its clinical significance is not settled, as no systematic review has addressed the prognostic significance of the increasingly prevalent high-sensitivity troponin assays in acute organ dysfunction setting. This study aims to clarify the association between early serum troponin levels in high-sensitivity assays with short-term mortality risk in septic patients with acute organ dysfunction.

Methods

We will systematically search PubMed, Scopus and Embase for original articles; additionally, a manual search will be carried out through relevan

SUBMITTER: Ferriere-Steinert S 

PROVIDER: S-EPMC11508495 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature