Euler Force-Driven Siphon Valve Control for Precise Sequential Release in Centrifugal Microfluidic Chips.

ABSTRACT: Controlling the fluids in centrifugal microfluidic chips for precise sequential release is critical for multi-step reactions and immunoassays. Currently, the traditional methods of liquid sequential release mainly rely on various types of microvalves, which face the problems of complex operation and high costs. Here, this work presents a method for driving liquid release using the Euler force. Under continuous acceleration and deceleration, the centrifugal and Euler forces can transfer the liquid from the sample chamber to the collection chamber. The liquid sequential release mechanism based on the Euler force was analyzed, which showed that the angular acceleration is key to the liquid release. Then, the geometrical parameters affecting the angular acceleration of complete release were in

SUBMITTER: Lu Y 

PROVIDER: S-EPMC11509089 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature