Efficacy of Virucidal Treatments against Poliovirus Type 1 Deposited on Stainless-Steel Carriers.

ABSTRACT: Safe containment of infectious poliovirus (PV) within Poliovirus-Essential Facilities (PEFs) will require the implementation of reliable PV-inactivation approaches for decontaminating work surfaces. Such approaches should be demonstrated empirically to display adequate efficacy at the use temperature, and the contact times required should be characterized to ensure efficacy. Such efficacy is judged by the ability of the inactivation approach to completely inactivate any PV deposited, with the demonstrated total log₁₀ reduction in PV titer being as high as empirically achievable. We screened several approaches for their efficacy in inactivating wild-type PV type 1 Chat strain experimentally deposited on stainless-steel carriers at room temperature. On the basis of the results, we

SUBMITTER: Chiossone C 

PROVIDER: S-EPMC11509370 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature