Proteome Expression Signatures: Differences between Orbital and Subcutaneous Abdominal Adipose Tissues.

ABSTRACT: Differences between orbital and subcutaneous abdominal fat in the same patient have been noted but not formally investigated, previously. The objective of this research was to compare the differential expression of protein profiles in subcutaneous abdominal and orbital adipose tissues. In this cross-sectional, observational study, orbital fat tissue was sampled from 10 patients who underwent blepharoplasty and agreed to provide a small sample of subcutaneous abdominal fat. Shotgun mass spectrometry was performed on the extracted proteome. Data were analyzed using protein appearance patterns, differential expression and statistical enrichment. Protein analysis revealed significant differences in proteomics and differential expression between the orbital and subcutaneous abdominal adipose ti

SUBMITTER: Castel N 

PROVIDER: S-EPMC11509502 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature