Heavy Metal and Trace Element Status and Dietary Determinants in Children with Phenylketonuria.

ABSTRACT: Background/Objectives: Heavy metals are a group of metals and metalloids that have a relatively high density. They can cause toxicity even at very low levels. Trace elements are required by all living organisms to maintain their normal growth, metabolism, and development. Oral intake is the main route of exposure to both heavy metals and trace elements. Phenylketonuria (PKU) is the most common amino acid metabolic disorder, and the best known treatment for patients requiring treatment is a phenylalanine (Phe)-restricted diet. The objective of the present study was to evaluate the plasma heavy metal levels, sources of exposure, changes in these levels according to dietary regimen, and trace element levels and their correlations with heavy metals in PKU patients. Methods: The s

SUBMITTER: Erdal I 

PROVIDER: S-EPMC11509891 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature