Outer Membrane Vesicles Formed by Clinical <i>Proteus mirabilis</i> Strains May Be Incorporated into the Outer Membrane of Other <i>P. mirabilis</i> Cells and Demonstrate Lytic Properties.

ABSTRACT: Outer membrane vesicles (OMVs) are extracellular structures, ranging in size from 10 to 300 nm, produced by Gram-negative bacteria. They can be incorporated into the outer membrane of a recipient's cells, which may enable the transfer of substances with lytic properties. Due to the scarce information regarding the OMVs produced by Proteus mirabilis, the aim of this study was to test the blebbing abilities of the clinical P. mirabilis O77 and O78 strains and to determine the blebs' interactions with bacterial cells, including their possible bactericidal activities. The production of OMVs was visualised by Transmission electron microscopy (TEM). The presence of OMVs in the obtained samples as well as the phenomenon of OMV fusion to recipient cells were confirmed by Enzyme-Linke

SUBMITTER: Szczerbiec D 

PROVIDER: S-EPMC11509992 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature