The Comprehensive Profiling of the Chemical Components in the Raw and Processed Roots of <i>Scrophularia ningpoensis</i> by Combining UPLC-Q-TOF-MS Coupled with MS/MS-Based Molecular Networking.

ABSTRACT: Scrophulariae Radix (SR), the dried root of Scrophularia ningpoensis Hemsl (S. ningpoensis), has been extensively used as traditional Chinese medicine for thousands of years. However, since the mid-20th century, the traditional processing technology of S. ningpoensis has been interrupted. Therefore, ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry technology, together with a Global Natural Product Social Molecular Networking (GNPS) method, was applied to comprehensively analyze the characteristic changes and mutual transformation of chemical constituents in the differently processed roots of S. ningpoensis, as well as to scientifically elucidate the processing mechanism of differently processed SR. As a result

SUBMITTER: Zhang M 

PROVIDER: S-EPMC11510058 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature