Safety Assessment and Evaluation of Probiotic Potential of <i>Lactobacillus bulgaricus</i> IDCC 3601 for Human Use.

ABSTRACT: Lactic acid bacteria (LAB) are probiotic microorganisms widely used for their health benefits in the food industry. However, recent concerns regarding their safety have highlighted the need for comprehensive safety assessments. In this study, we aimed to evaluate the safety of L. bulgaricus IDCC 3601, isolated from homemade plain yogurt, via genomic, phenotypic, and toxicity-based analyses. L. bulgaricus IDCC 3601 possessed a single circular chromosome of 1,865,001 bp, with a GC content of 49.72%, and 1910 predicted coding sequences. No virulence or antibiotic resistance genes were detected. Although L. bulgaricus IDCC 3601 exhibited antibiotic resistance to gentamicin and kanamycin, this resistance is an intrinsic feature of this species. L. bulgaricus IDCC 360

SUBMITTER: Lee M 

PROVIDER: S-EPMC11510087 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature