The Potential Role of Boron in the Modulation of Gut Microbiota Composition: An In Vivo Pilot Study.

ABSTRACT: Background/Objectives: The role of the gut microbiome in the development and progression of many diseases has received increased attention in recent years. Boron, a trace mineral found in dietary sources, has attracted interest due to its unique electron depletion and coordination characteristics in chemistry, as well as its potential role in modulating the gut microbiota. This study investigates the effects of inorganic boron derivatives on the gut microbiota of mice. Methods: For three weeks, boric acid (BA), sodium pentaborate pentahydrate (NaB), and sodium perborate tetrahydrate (SPT) were dissolved (200 mg/kg each) in drinking water and administered to wild-type BALB/c mice. The composition of the gut microbiota was analyzed to determine the impact of these treatments. <

SUBMITTER: Senturk NB 

PROVIDER: S-EPMC11510266 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature