<i>Limosilactobacillus reuteri</i> DSM 17938 Produce Bioactive Components during Formulation in Sucrose.

ABSTRACT: Improved efficacy of probiotics can be achieved by using different strategies, including the optimization of production parameters. The impact of fermentation parameters on bacterial physiology is a frequently investigated topic, but what happens during the formulation, i.e., the step where the lyoprotectants are added prior to freeze-drying, is less studied. In addition to this, the focus of process optimization has often been yield and stability, while effects on bioactivity have received less attention. In this work, we investigated different metabolic activities of the probiotic strain Limosilactobacillus reuteri DSM 17938 during formulation with the freeze-drying protectant sucrose. We discovered that the strain consumed large quantities of the added sucrose and produced an exo

SUBMITTER: Ermann Lundberg L 

PROVIDER: S-EPMC11510291 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature