<i>Capparis sepiaria</i>-Loaded Sodium Alginate Single- and Double-Layer Membrane Composites for Wound Healing.

ABSTRACT: Background: Effective wound dressing is the key solution to combating the increased death rate and prolonged hospital stay common to patients with wounds. Methods: Sodium alginate-based single- and double-layer membranes incorporated with Capparis sepiaria root extract were designed using the solvent-casting method from a combination of polyvinyl alcohol (PVA), Pluronic F127 (PF127), and gum acacia. Results: The successful preparation of the membranes and loading of the extract were confirmed using Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The prepared membranes were biodegradable and non-toxic to human skin cells (HaCaT), with high biocompatibility of 92 to 112% cell viability and good hemocompatibility with absorbance ranging

SUBMITTER: Ndlovu SP 

PROVIDER: S-EPMC11510319 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature