Schistosomiasis-Microbiota Interactions: A Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Schistosomiasis, a tropical disease affecting humans and animals, affected 251.4 million people in 2021. Schistosoma mansoni, S. haematobium, S. intercalatum, and S. japonicum are primary human schistosomes, causing tissue damage, granulomas, ulceration, hemorrhage, and opportunistic pathogen entry. The gut and urinary tract microbiota significantly impact a host's susceptibility to schistosomiasis, disrupting microbial balance; however, this relationship is not well understood. This systematic review and meta-analysis explores the intricate relationship between schistosomiasis and the host's microbiota, providing crucial insights into disease pathogenesis and management.

Methods

This systematic review used PRISMA guidelines to identi

SUBMITTER: Afful P 

PROVIDER: S-EPMC11510367 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature